The Ejsing Lab is situated at the University of Southern Denmark (SDU) [Odense, Denmark] and also at the European Molecular Biology Laboratory (EMBL) [Heidelberg, Germany].
Our research is primarily focused on:
► development and applications of mass spectrometry-based lipidomics techniques that allow global analysis of cellular lipidomes and lipid metabolic flux
► combining lipidomics techniques with other -OMICS technologies (incl. proteomics and phosphoproteomics) to perform systems biology studies of the regulation of lipid metabolism in cells and animals (systemic regulation)
► clinical lipidomics with the aim of identifying lipid biomarkers for monitoring metabolic health
Mass spectrometry-based lipidomics is a powerful tool for characterizing the molecular lipid composition of cells and tissues. In comparison with traditional methods such as thin-layer chromatography and liquid chromatography, lipidomics offer unsurpassed sensitivity and structural resolution at the level of individual lipid species. Lipidomics techniques can be executed to provide lipidome-wide quantitative assessment of global perturbations promoted by physiological and pathological stimuli.